On a U-100 insulin syringe, 1 mg of semaglutide is 100 units at 1 mg/mL, 50 units at 2 mg/mL, 40 units at 2.5 mg/mL, 25 units at 4 mg/mL, 20 units at 5 mg/mL, 10 units at 10 mg/mL.

At 2.5 mg/mL, the strength most often seen on compounded labels, it is 0.4 mL, which is 40 units. Use the calculator with the strength printed on your own vial.

1 mg of semaglutide in units at every strength

1 mg of semaglutide at every vial strength, on a U-100 insulin syringe. Listed doses are for conversion only. Your prescriber sets your dose.
Vial strengthVolumeUnits (U-100)
1 mg/mL1 mL100 units
2 mg/mL0.5 mL50 units
2.5 mg/mL0.4 mL40 units
4 mg/mL0.25 mL25 units
5 mg/mL0.2 mL20 units
10 mg/mL0.1 mL10 units

Dose ↔ units

Vial type

I know my…

How long will my vial last?

Uses the vial and dose from the calculator above.

Real vials can hold slightly more or less than the label says, and a little is lost in the needle.

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Same dose, different units

At 2.5 mg/mL, 1 mg is 40 units. Drawing those same 40 units from a 5 mg/mL vial gives 2 mg, not 1 mg. Always check the mg/mL on the vial you are using.

In July 2024 the FDA warned about dosing errors with compounded semaglutide, including mix-ups between mg, mL and units (FDA alert). The same math applies to any vial.

Questions

How many mL is 1 mg of semaglutide?

It depends on the vial: 1 mL at 1 mg/mL, 0.5 mL at 2 mg/mL, 0.4 mL at 2.5 mg/mL, 0.25 mL at 4 mg/mL, 0.2 mL at 5 mg/mL, 0.1 mL at 10 mg/mL.

Is 1 mg of semaglutide the same number of units on every vial?

No. The units depend on the strength printed on the vial: 100 units at 1 mg/mL, 50 units at 2 mg/mL, 40 units at 2.5 mg/mL, 25 units at 4 mg/mL, 20 units at 5 mg/mL, 10 units at 10 mg/mL.

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