Semaglutide 4 mg/mL Dosage Chart in Units (U-100)

At 4 mg/mL, every 10 units on a U-100 syringe is 0.4 mg of semaglutide.

0.25 mg is 6.3 units, and 0.5 mg is 12.5 units. Use the calculator for any other amount.

Dose ↔ units

Vial type Liquid vial (strength on label) Powder vial (I add water)

Strength (mg/mL)

I know my… Dose in mg Units

Dose (mg)

Syringe

How long will my vial last?

Uses the vial and dose from the calculator above.

Real vials can hold slightly more or less than the label says, and a little is lost in the needle.

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Semaglutide 4 mg/mL dose to units chart

Semaglutide 4 mg/mL: dose to units on a U-100 insulin syringe. Listed doses are for conversion only. Your prescriber sets your dose.
Dose	Volume	Units (U-100)
0.25 mg	0.063 mL	6.3 units
0.5 mg	0.125 mL	12.5 units
1 mg	0.25 mL	25 units
1.5 mg	0.375 mL	37.5 units
1.7 mg	0.425 mL	42.5 units
2 mg	0.5 mL	50 units
2.4 mg	0.6 mL	60 units

Semaglutide 4 mg/mL units to mg chart

Semaglutide 4 mg/mL: units to mg
Units (U-100)	Volume	Dose
5 units	0.05 mL	0.2 mg
10 units	0.1 mL	0.4 mg
15 units	0.15 mL	0.6 mg
20 units	0.2 mL	0.8 mg
25 units	0.25 mL	1 mg
30 units	0.3 mL	1.2 mg
35 units	0.35 mL	1.4 mg
40 units	0.4 mL	1.6 mg
45 units	0.45 mL	1.8 mg
50 units	0.5 mL	2 mg
55 units	0.55 mL	2.2 mg
60 units	0.6 mL	2.4 mg
65 units	0.65 mL	2.6 mg
70 units	0.7 mL	2.8 mg
75 units	0.75 mL	3 mg
80 units	0.8 mL	3.2 mg
85 units	0.85 mL	3.4 mg
90 units	0.9 mL	3.6 mg
95 units	0.95 mL	3.8 mg
100 units	1 mL	4 mg

How long a 4 mg/mL vial lasts

Semaglutide 4 mg/mL: full weekly doses per vial (leftover in brackets). Listed doses are for conversion only. Your prescriber sets your dose.
Vial	Total	0.25 mg doses	0.5 mg doses	1 mg doses	1.5 mg doses	1.7 mg doses	2 mg doses	2.4 mg doses
1 mL	4 mg	16	8	4	2 (+1 mg)	2 (+0.6 mg)	2	1 (+1.6 mg)
2 mL	8 mg	32	16	8	5 (+0.5 mg)	4 (+1.2 mg)	4	3 (+0.8 mg)
3 mL	12 mg	48	24	12	8	7 (+0.1 mg)	6	5
4 mL	16 mg	64	32	16	10 (+1 mg)	9 (+0.7 mg)	8	6 (+1.6 mg)
5 mL	20 mg	80	40	20	13 (+0.5 mg)	11 (+1.3 mg)	10	8 (+0.8 mg)

Real vials can hold slightly more or less than the label says, and a little is lost in the needle.

Notes for 4 mg/mL

At 4 mg/mL, 1 unit is 0.04 mg and 10 units is 0.4 mg.
Listed doses up to 2 mg fit a 0.5 mL (50-unit) syringe.
Listed doses up to 1 mg fit a 0.3 mL (30-unit) syringe.

Check the strength on every new vial

Units only mean something for one strength. If 20 units was 0.5 mg on a 2.5 mg/mL vial, the same 20 units from a 4 mg/mL vial is 0.8 mg, not 0.5 mg.

In July 2024 the FDA warned about dosing errors with compounded semaglutide, including mix-ups between mg, mL and units (FDA alert). The same math applies to any vial.

Questions

How many units is 0.25 mg of semaglutide at 4 mg/mL?

0.063 mL, which is 6.3 units on a U-100 insulin syringe.

How many units is 0.5 mg of semaglutide at 4 mg/mL?

0.125 mL, which is 12.5 units on a U-100 insulin syringe.

How many mg is 10 units of semaglutide at 4 mg/mL?

10 units is 0.1 mL, which is 0.4 mg at this strength.

How many 0.5 mg doses are in a 2 mL vial of 4 mg/mL semaglutide?

A 2 mL vial at 4 mg/mL holds 8 mg: 16 full doses of 0.5 mg.

Semaglutide 4 mg/mL dosage chart in units